Continuing ZEJULA

If you’ve already started ZEJULA or have been taking it for some time, these tips and advice are for you.

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Keep partnering with your doctor

You may not be seeing your healthcare team as much as you did previously, so you’ll want to make sure you keep them updated. Questions? Changes in how you’re feeling? Concerns? They’re here for you.

 

Here are some ways you could start the conversation:

  • What are some things I could do to make sure I’m prioritizing my health?
  • I’ve been feeling (fill in the blank) recently; could this be ZEJULA-related?
  • Is there anything else I should know now that I’ve been taking ZEJULA for a while?
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Remember your “why”

It may be helpful to think back to when you chose ZEJULA and what motivated your decision. The questions that follow may help you stay on track and uncover what matters most to you.

Ask yourself:

  • What are some of your personal reasons for starting ZEJULA?
  • Why are these reasons meaningful for you?
  • Which of these motivate you the most?
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Check in on your ZEJULA routine

Are you managing to take ZEJULA at the same time every day? If not, think about what time of day would work better for you, and take it at that time each day. Consider how you will remember on days when you have a different schedule, like a vacation or a day with an appointment. Remember to keep following your doctor's schedule for routine monitoring.

 

Talk to your healthcare team about any challenges you may be having.

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Know you’re in good company

Even with a wonderful support system, sometimes it can feel like you’re the only one going through this. And while each experience is unique, it can be reassuring to know you’re not alone. Alongside you are thousands of patients taking ZEJULA.

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Have you signed up for ZEJULA My Way yet?

ZEJULA My Way is our patient support program, which delivers timely support and resources designed to meet you where you are.

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Looking for assistance paying for ZEJULA?

Whether you’re uninsured or insured, Together with GSK Oncology may be able to provide information and options for paying for ZEJULA.

Approved Uses & Safety Info

Approved Uses

ZEJULA is a prescription medicine used for the:

  • maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.
  • maintenance treatment of adults with a certain type of inherited (germline) abnormal BRCA gene with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy. Your healthcare provider will perform a test to make sure that ZEJULA is right for you.  

 

It is not known if ZEJULA is safe and effective in children.

Important Safety Information

ZEJULA may cause serious side effects, including:

 

Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with ZEJULA. MDS or AML may lead to death.

 

Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with ZEJULA. They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:

  • Weakness
  • Feeling tired
  • Weight loss
  • Frequent infections
  • Fever
  • Shortness of breath
  • Blood in urine or stool
  • Bruising or bleeding more easily


Your doctor will do blood tests to check your blood cell counts before treatment with ZEJULA. You will be tested weekly for the first month of treatment with ZEJULA, monthly for the next 11 months of treatment, and as needed afterward.

 

High blood pressure is common during treatment with ZEJULA, and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with ZEJULA.

 

Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with ZEJULA. If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.

 

Before starting to take ZEJULA, tell your doctor about all of your medical conditions, including if you:

  • Have heart problems
  • Have liver problems
  • Have high blood pressure
  • Are pregnant or plan to become pregnant. ZEJULA can harm your unborn baby and may cause loss of pregnancy (miscarriage)
    • If you are able to become pregnant, your doctor should perform a pregnancy test before you start treatment with ZEJULA
    • If you are able to become pregnant, you should use effective birth control (contraception) during treatment with ZEJULA and for 6 months after taking the last dose of ZEJULA
    • You should tell your doctor right away if you become pregnant
  • Are breastfeeding or plan to breastfeed
    • ZEJULA may harm your baby. You should not breastfeed your baby during treatment with ZEJULA and for 1 month after taking the last dose of ZEJULA


Tell your doctor about all the medicines you take,
 including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

The most common side effects of ZEJULA include the following:

  • Nausea
  • Tiredness
  • Constipation
  • Pain in your muscles and back
  • Pain in the stomach area
  • Vomiting
  • Loss of appetite
  • Trouble sleeping
  • Headache
  • Shortness of breath
  • Rash
  • Diarrhea
  • Cough
  • Dizziness
  • Changes in the amount or color of your urine
  • Urinary tract infection
  • Low levels of magnesium in the blood


If you have certain side effects, then your doctor may change your dose of ZEJULA, temporarily stop, or permanently stop treatment with ZEJULA.

 

These are not all the possible side effects of ZEJULA. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

 

Please see accompanying full Prescribing Information for ZEJULA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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Explore the GSK Help Center website to find customer service support and contact information.

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If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).