Taking ZEJULA (niraparib)

Learn how to take, store, and keep track of your treatment with ZEJULA

ZEJULA is a once-daily oral medication, which may make it easy to fit into your schedule. So you can plan your treatment around your life—not your life around your treatment.

Daughter with mother taking ZEJULA (niraparib)

Monitoring how your body responds

 

Your healthcare provider will keep a close eye on how ZEJULA is affecting you. He or she will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during treatment with ZEJULA.

 

Your doctor will also regularly monitor your blood cell counts because ZEJULA can cause changes in your blood cell levels. Complete blood cell counts will be monitored weekly for the first month, monthly for the next 11 months, and periodically after that to ensure that your doctor can respond quickly to any changes.

WHAT WILL BE MONITORED HOW OFTEN
Blood pressure Weekly for the first 2 months*
Monthly for the first year*
As needed after 12 months*
Heart rate Weekly for the first 2 months*
Monthly for the first year*
As needed after 12 months*
Blood cell counts Weekly for the first month*
Monthly for the next 11 months*
As needed after 12 months*

*Schedule provided as an example.
Your doctor will determine how often you need blood work.

Keep in mind:

 

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While ZEJULA should be taken at approximately the same time each day, you can choose a time that’s convenient for you

 

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ZEJULA can be taken with or without food, which means that you’re not tied to meal schedules

 

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If you miss a dose or vomit after taking a dose of ZEJULA, take the next dose at your regularly scheduled time. Do not take an extra dose

 

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ZEJULA is easy to travel with. You can keep it with you on the go in a purse or bag

 

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Store ZEJULA at room temperature (between 68°F and 77°F)

 

ZEJULA (niraparib) pill bottle

ZEJULA Dosing Recommendations



MAINTENANCE FOR NEWLY DIAGNOSED
ADVANCED OVARIAN CANCER
200 mg/day
OR
300 mg/day
Your doctor will
evaluate your baseline
weight and platelet
count to determine the
appropriate starting
dose for you.
MAINTENANCE FOR RECURRENT OVARIAN CANCER /
TREATMENT AFTER 3+ CHEMOTHERAPY REGIMENS
300 mg/day

 

Before taking ZEJULA, tell your doctor about all of your medical conditions. Your doctor may determine that the appropriate starting dose is 200 mg if you have liver problems.

By working with your doctor to customize your dose of ZEJULA, you may be able to stay on and benefit from treatment longer.

Couple walking outside

Managing potential side effects

 

It’s important to tell your doctor about any side effects that you experience while taking ZEJULA. Together, you can work to find the right dose for you. For example, if you experience nausea, your doctor may suggest taking ZEJULA before bed.

 

If you experience side effects, your doctor may interrupt your treatment with ZEJULA for up to 28 days or reduce the number of capsules that you take each day. This dose adjustment or interruption is to allow your blood counts or other severe side effects to improve. Your doctor may ask you to make adjustments in the schedule of your blood tests and will determine when you can resume taking ZEJULA.

 

LEARN MORE ABOUT ZEJULA SIDE EFFECTS

Frequently Asked
Questions

How do I take ZEJULA?

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What should I do if I experience a side effect?

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What is a dose adjustment? Why might my dose be adjusted?

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