Taking ZEJULA (niraparib) tablets

Learn how to take and store your ZEJULA

ZEJULA comes as one tablet once daily, which may make it easy to fit into your schedule. So you can plan your treatment around your life—not your life around your treatment.

Daughter with mother taking ZEJULA (niraparib)

Not actual ZEJULA patients. ZEJULA is not indicated in patients under 18.

Monitoring how your body responds


Your healthcare provider will keep a close eye on how ZEJULA is affecting you. He or she will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during treatment with ZEJULA.


Your doctor will also regularly monitor your blood cell counts because ZEJULA can cause changes in your blood cell levels. Complete blood cell counts will be monitored weekly for the first month, monthly for the next 11 months, and periodically after that to ensure that your doctor can respond quickly to any changes.

Blood pressure Weekly for the first 2 months*
Monthly for the first year*
As needed after 12 months*
Heart rate Weekly for the first 2 months*
Monthly for the first year*
As needed after 12 months*
Blood cell counts Before treatment with ZEJULA*
Weekly for the first month*
Monthly for the next 11 months*
As needed after 12 months*

*Please follow your doctor’s instructions for monitoring requirements.
After 12 months, your doctor will determine how often you need to check your blood pressure, heart rate, and blood cell counts.

Keep in mind:


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While ZEJULA should be taken at approximately the same time each day, you can choose a time that’s convenient for you


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ZEJULA can be taken with or without food, which means you’re not tied to meal schedules and can take it alongside a daily activity like brushing your teeth


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If you miss a dose or vomit after taking a dose of ZEJULA, take the next dose at your regularly scheduled time. Do not take an extra dose


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Always swallow your ZEJULA tablet whole; do not crush, chew, or split your tablet


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Store ZEJULA tablets in the original bottle and at room temperature (between 68°F and 77°F) 


ZEJULA (niraparib) tablet bottles

ZEJULA dosage forms and strengths


  • 300 mg

    Once-Daily 300 mg Tablet


    (not actual size)

  • 200 mg

    Once-Daily 200 mg Tablet


    (not actual size)

  • 100 mg

    Once-Daily 100 mg Tablet


    (not actual size)


Before taking ZEJULA, tell your doctor about all of your medical conditions. Your doctor can determine the appropriate starting dose for you.

Your doctor will determine the appropriate dose based on your medical history. Your dose may be customized to you, which may help with certain side effects.

Couple walking outside

Not an actual ZEJULA patient.

Managing potential side effects


It’s important to tell your doctor about any side effects that you experience while taking ZEJULA. Together, you can work to find the right dose for you. For example, if you experience nausea, your doctor may suggest taking ZEJULA before bed.


If you experience side effects, your doctor may interrupt your treatment with ZEJULA for up to 28 days or reduce your daily dose. This dose adjustment or interruption is to allow your blood counts or other severe side effects to improve. Your doctor may ask you to make adjustments in the schedule of your blood tests and will determine when you can resume taking ZEJULA.



Frequently Asked

How do I take ZEJULA?


What should I do if I experience a side effect?


What is a dose adjustment? Why might my dose be adjusted?