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A Guide to Treatment

This is the place to get a clear idea on what maintenance therapy with ZEJULA may look like.

Starting treatment with ZEJULA

We’ve gathered some initial topics to explore

Find out how you’ll receive ZEJULA

You may receive ZEJULA from a specialty pharmacy or through your doctor’s associated hospital or clinic.

GET MORE DETAILS
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Get to know monitoring requirements

Your healthcare team will monitor your body’s response to ZEJULA with periodic blood tests, blood pressure and heart rate checks.

SEE MONITORING SPECIFICS
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Familiarize yourself with potential side effects

You may experience side effects while taking ZEJULA. It's important to discuss these with your healthcare team before taking ZEJULA.

KNOW POTENTIAL SIDE EFFECTS
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See how to take ZEJULA

ZEJULA is one tablet, once daily, taken at approximately the same time each day; you can choose a time that fits into your schedule.

EXPLORE DOSING
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There’s never been a better time to focus on you

Putting it lightly, you’ve been through a lot. In your new day-to-day after chemo, you might not find yourself jumping right back into the things you did before. Your perspectives may have changed. Your support needs could look a little different. But this can also be a great time to focus on yourself.

SEE SELF-CARE TIPS

When taking on a new step, more info can be helpful!

 

Sign up for ZEJULA My Way to get support and resources tailored to where you are in your journey—whether that’s just starting out with ZEJULA or considering it. One way to tackle uncertainty is to get all the info you can!

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Questions about ZEJULA?

Click below for helpful information.

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Understanding side effects

Learn what to look for and how to partner with your healthcare team to address potential side effects.

Approved Uses & Safety Info

Approved Uses

ZEJULA is a prescription medicine used for the:

  • maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.
  • maintenance treatment of adults with a certain type of inherited (germline) abnormal BRCA gene with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy. Your healthcare provider will perform a test to make sure that ZEJULA is right for you.  

 

It is not known if ZEJULA is safe and effective in children.

Important Safety Information

ZEJULA may cause serious side effects, including:

 

Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with ZEJULA. MDS or AML may lead to death.

 

Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with ZEJULA. They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:

  • Weakness
  • Feeling tired
  • Weight loss
  • Frequent infections
  • Fever
  • Shortness of breath
  • Blood in urine or stool
  • Bruising or bleeding more easily


Your doctor will do blood tests to check your blood cell counts before treatment with ZEJULA. You will be tested weekly for the first month of treatment with ZEJULA, monthly for the next 11 months of treatment, and as needed afterward.

 

High blood pressure is common during treatment with ZEJULA, and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with ZEJULA.

 

Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with ZEJULA. If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.

 

Before starting to take ZEJULA, tell your doctor about all of your medical conditions, including if you:

  • Have heart problems
  • Have liver problems
  • Have high blood pressure
  • Are pregnant or plan to become pregnant. ZEJULA can harm your unborn baby and may cause loss of pregnancy (miscarriage)
    • If you are able to become pregnant, your doctor should perform a pregnancy test before you start treatment with ZEJULA
    • If you are able to become pregnant, you should use effective birth control (contraception) during treatment with ZEJULA and for 6 months after taking the last dose of ZEJULA
    • You should tell your doctor right away if you become pregnant
  • Are breastfeeding or plan to breastfeed
    • ZEJULA may harm your baby. You should not breastfeed your baby during treatment with ZEJULA and for 1 month after taking the last dose of ZEJULA


Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

The most common side effects of ZEJULA include the following:

  • Nausea
  • Tiredness
  • Constipation
  • Pain in your muscles and back
  • Pain in the stomach area
  • Vomiting
  • Loss of appetite
  • Trouble sleeping
  • Headache
  • Shortness of breath
  • Rash
  • Diarrhea
  • Cough
  • Dizziness
  • Changes in the amount or color of your urine
  • Urinary tract infection
  • Low levels of magnesium in the blood


If you have certain side effects, then your doctor may change your dose of ZEJULA, temporarily stop, or permanently stop treatment with ZEJULA.

 

These are not all the possible side effects of ZEJULA. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

 

Please see accompanying full Prescribing Information for ZEJULA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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Explore the GSK Help Center website to find customer service support and contact information.

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If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).